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In this month's issue of Extracts Facts email newsletter, we discuss the recent marketing buzz about the hottest herb from the arctic regions of the north. Read all about Rhodiola rosea and its wide ranging adaptogenic properties. This could be the next superstar herb!


If you missed our last issue, be sure to link to it here! Included is an article about Dodder Seed, a powerful male sexual enhancement herb.

Also, Draco's marketing guy goes to the new Draco manufacturing facility in Shanghai, China and returns with a boatload of photos. See the facility firsthand in his special trip report.


Rhodiola rosea
Cold Region Herb with Hot Market Potential

2 years ago, we distributed an issue of our Extrax Fax newsletter on the subject of the herb Rhodiola rosea entitled "Rhodiola Radix: The Most Useful Herb You've Never Heard Of" (See article) At that point in time, the herb really was for the most part unknown, despite a decade of effort on the part of the Swedish Herbal Institute to popularize it as Arctic Root. But since then, our friends at ABC published a seminal piece on Rhodiola in a recent issue of Herbalgram (see reference below) giving an excellent detailed overview of the phytomedicinal properties of the plant. Then Anne Underwood from Newsweek Magazine got a hold of the article and Newsweek printed a one-page story about the herb in their February 3rd 2003 issue. Needless to say, the attention has generated some marketing buzz, but it is still too early to tell if much of it is catching on with consumers.

Why all the excitement about Rhodiola? As it turns out, this northern Asian root packs a potent adaptogenic punch, helping the body to adapt to 21st century living in many ways. As ABC's Mark Blumenthal told Newsweek's Ms. Underwood, "It's got everything to become an herbal superstar - a high safety profile, compelling benefits and a reasonable amount of scientific research." In fact, it has been treasured in Russia and Sweden for many hundreds of years for increasing mental focus, physical endurance, productivity and fertility while fighting depression, fatigue, impotence, hypoxia, anemia, infections and even cancer.

Rhodiola rosea is a member of a 50-species genus of plants with northern hemisphere distribution. The genus is closely related to the Sedum that is popular in American gardens. Rhodiola rosea itself is native to the northern latitudes and arctic regions of Asia and Europe (Scandinavia and Siberia), but is also found in China at elevations above 3,300 meters. It is the rootstock of this perennial that is harvested and most commonly extracted as either a tincture or dry extract.

Manufacturers should be aware that of all the Rhodiolas, it is only the rosea species that contains the active constituents that make it a valued adaptogen. As with other medicinal herbs, the specific compounds thought to be responsible for Rhodiola's health benefits has shifted over the course of its discovery. In the 1970's, a phenylethanol derivative called salidroside was thought to be the primary active. More recently, attention has focused on its phenylpropanoid constitituents: rosavin, rosin, and rosarin, called collectively "rosavins". Brown, Gerbarg & Ramazanov in the Herbalgram article (ref) point out that while rosavin content is a useful marker, precise identification of all the true actives remains a mystery. Using a whole herb extract of the root containing a full representation of plant constituents is a wise and effective approach to ensuring a quality product.

It is important to note that when a supplier uses an extraction process designed to concentrate only the rosavins in the final extract, other important constituents may begin to drop out of the mix. In line with our overall manufacturing philosophy, we have found that a full spectrum Rhodiola rosea product is more therapeutically efficacious than a concentrated one and we are careful to preserve the natural balance of constituents. We do, however, standardize to marker compounds.

Rhodiola rosea is an authentic adaptogen, non-specifically increasing the resistance of the body without disturbing its normal biological functions. For that reason, it is a great herb for combating stress. It is theorized that R. rosea improves the brain's ability to deal with stress by 1) increasing serotonin in the hypothalamus and midbrain, 2) increasing endorphins, 3) moderating the release of opioid peptides that occur as a part of the stress response, and 4) protecting the brain and heart by reducing the stress related production of corticotrophin releasing factor (CRF).

It is a wonderful herb for mental focus and cerebral activity. It promotes the release and enhances the effectiveness of neurotransmitters like serotonin, dopamine and norepinephrine in the brain. The results, demonstrated in several clinical studies, are enhanced mental performance, learning, attention span, and memory. It has been widely used as an antidepressant, working alone or adjunctively with other antidepressants. Because of the breadth of its adaptogenic effects, some patients find it more effective than prescription SSRI's or St. John's Wort.

Another beneficial adaptogenic effect of Rhodiola rosea is its ability to increase physical work capacity, improving strength, recovery time, endurance, and coordination. Clinical studies found it to be more effective than Eleuthero at enhancing adaptation to physical stress. Combining the two herbs in a formula is even better, as R. rosea and Eleutherococcus senticosis are very compatible, producing beneficial synergistic effects.

Rhodiola has been shown to enhance fertility in women, even among those that have failed to conceive with standard fertility drugs; and to substantially improve sexual performance in men with erectile dysfunction and/or premature ejaculation. It also enhances thyroid and adrenal function without causing hyperfunction of those organs.

Part of R. rosea's effectiveness as a stress adaptogen is due to its cardioprotective effects. Because it promotes the balanced release of epinephrine and nor epinephrine, it is a very effective anti-arrhythmia/tachycardia agent. It also increases the energy efficiency and energy reserves of the heart by balancing the heart's sympathetic and parasympathetic autonomic nerve inputs.

Additionally, this amazing root is a strong antioxidant with several anti-cancer effects. It reduces the toxicity of anti-cancer drugs and enhances their anti-carcinogenic effects. It helps to inhibit tumor growth on its own, and is also anti-mutagenic, substantially reducing the development of chromosomal aberrations.

R. rosea is very safe with very low toxicity and few side effects. It is best taken early in the day because its mental activation effects can interfere with sleep. It is a potent herb and is useful at low dosage levels (50-200mg/day of extract), depending on the desired effect. At lower doses, the herb is stimulating; at higher doses, more sedating.

With such a huge cornucopia of beneficial effects, we agree with Mr. Blumenthal that this should be a superstar herb. If enough people are educated about Rhodiola rosea's many effects, it is likely that it will be used widely for stress reduction, mental focus, depression, endurance, fertility and even cancer treatment.

We are ready to supply you with Draco Full Spectrum Standardized™ Rhodiola rosea herbal extract, standardized to specific marker compounds. This is an exceptionally potent product with a typical efficacy range of only 50mg to 100mg per dose. Draco's products and process are ISO9000 and Kosher certified. Please call us at (408)287-7871 for more details!

References
Brown, Richard P. M.D., Patricia L. Gerbarg,M.D., and Zakir Ramazanov, Ph.D., D.S. "Rhodiola rosea: A Phytomedicinal Overview" Herbalgram, No. 56, 2002.

Underwood, Anne. "Health: The Herbal Stress Buster? Can a Russian Root Be Good For Your Health?" Newsweek, Feb 3, 2003.

© Copyright 2003, Draco Natural Products, Inc.
All Rights Reserved.


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